Physical Traits

Double-Fold Eyelids gene explained

Could your DNA reveal your Double-Fold Eyelids? Upload raw DNA data to learn more about yourself and genomics science.


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How are "Double-Fold Eyelids" encoded by the genome?

Double-fold eyelid, also known as hooded eyelids, where there is a crease are en vogue in Asian countries; everyone seems to want them. Glues to create double-fold eyelids are becoming part of the standard makeup routine. But for those who prefer a more permanent solution, surgery to create double-fold eyelids is an increasingly popular option, with over 40,000 Japanese women undergoing the procedure each year.

In a genome-wide association study of over 11,000 Japanese women, investigators found some new gene loci associated with double-fold eyelids. Interestingly, the loci were associated with a gene that has been previously found to be important in skeletal and neural development (which are components that are important to facial structure development in the embryo). To find out more, read the study here: https://www.ncbi.nlm.nih.gov/pubmed/29895819

To what extent does your DNA explain the folds of your eyelids (or lack thereof)? Find out on Genomelink!

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