Lung Cancer Genetics: What to Know
Lung cancer is a devastating disease that claims hundreds of thousands of lives each year. Of course, smoking is one of the most well-known risk factors, but there is growing interest in understanding the hereditary aspect of lung cancer, and how it might play into your health outcome – smoker or not. As a result, more people are asking the question: Is lung cancer hereditary? Lung cancer DNA research is a valuable tool for identifying gene mutations that may increase the risk of developing lung cancer down the line. If you know the lung cancer gene mutation runs in your family or have reason to believe you might be more susceptible, you may want to pursue lung cancer genetic testing in order to explore the odds a little deeper – and to act preventatively in the meantime.
Is Lung Cancer Hereditary? Common Symptoms of Lung Cancer
Recognizing the symptoms of lung cancer is crucial for early detection and treatment. Although the symptoms may vary depending on the stage and type of cancer, some common indicators include persistent coughing, chest pain, shortness of breath, hoarseness, unexplained weight loss, fatigue, and recurring respiratory infections. However, it's important to note that these symptoms can also be attributed to other less severe conditions – and you may still be at risk for the lung cancer gene mutation despite displaying none of these symptoms. Because of these factors, it’s a good idea to consult a healthcare professional for proper evaluation and diagnosis of the illness.
Is Lung Cancer Hereditary?
You may be wondering: is lung cancer hereditary? – especially if the lung cancer gene mutation definitely runs in your family. But it isn’t always so straightforward. Often, the answer lies somewhere in the relationship between genetics and environmental factors. While smoking is the primary cause of lung cancer, researchers have discovered certain lung cancer gene mutations that can increase an individual's susceptibility to the disease. These mutations can be inherited from parents or occur spontaneously throughout the course of a person's lifetime.
Reasons to Pursue Lung Cancer DNA Research
Lung cancer genetic research can provide valuable insights for individuals who have a family history of the lung cancer gene mutation, or who have been diagnosed at a relatively young age. Here are some main reasons why someone might consider pursuing lung cancer genetic testing – especially if they’ve been asking themselves the question: Is lung cancer hereditary?
- Family History
If your family has a history of the lung cancer gene mutation – especially in first-degree relatives – you might want to pursue lung cancer DNA testing to determine your risk. Identifying specific gene mutations can help inform preventive measures you should be taking, and enable early detection to allow you to make those decisions in as timely a manner as possible.
- Early-Onset Diagnosis
Lung cancer is typically found in older people. However, it’s not impossible to be diagnosed with lung cancer at a young age, and if that’s the case for you, the results may suggest an inherited genetic predisposition. Lung cancer DNA testing can identify lung cancer gene mutations that contribute to the development of the disease, which can either help you today, or help your family’s descendants tomorrow.
- Treatment Options
Certain gene mutations, such as EGFR, are associated with specific targeted therapies that can improve treatment outcomes.
- Family Planning
With that idea in mind: if you’re considering starting a family, you may opt for genetic testing to understand your risk of passing on gene mutations associated with lung cancer to your children. This knowledge can help you make informed decisions about reproduction, and seek appropriate medical advice where necessary.