Could your DNA reveal your Sagging Eyelids

Genetic underpinnings of one sign of age

In this article, we're looking at the genetic underpinnings of one sign of age: sagging eyelids. Unfortunately, sagging eyelids may not only be a cosmetic sign of aging: it has also been associated with eye problems, such as eye irritation and certain visual disorders. It is also a very heritable trait: if you have noticed that your parents or grandparents have sagging eyelids, you are likely to have them as well.

From a genome-wide association study involving older Caucasian women living in Paris, we are starting to understand the genetics of eyelid sagging. The study, which controlled for other factors influencing sagging eyelids such as age and smoking habits, identified that two gene loci on chromosome 10 are associated with the extent of eyelid sagging. These two loci are found in a gene that has been associated with aging, and having a specific variant at the loci can prevent your eyelids from sagging. Check this link for more details: https://www.ncbi.nlm.nih.gov/pubmed/?term=29654602

Are you genetically more likely to have sagging eyelids? Check Genomelink to find out!